Thr184
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Home > Phosphorylation Site Page: > Thr184  -  TAK1 (rat)

Site Information
GTACDIQtHMtNNKG   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 454876

In vivo Characterization
Methods used to characterize site in vivo:
immunoassay ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
aorta ( 1 ) , VSMC ('muscle, smooth') ( 1 )

Upstream Regulation
Treatments:
injury ( 1 ) , PDGF ( 1 ) , TAK1_inhibitor ( 1 )

Downstream Regulation
Effects of modification on TAK1:
enzymatic activity, induced ( 1 )
Effects of modification on biological processes:
autophagy, induced ( 1 ) , cell cycle regulation ( 1 ) , cell growth, induced ( 1 ) , cell motility, induced ( 1 )

References 

1

Zheng X, et al. (2022) TAK1 accelerates transplant arteriosclerosis in rat aortic allografts by inducing autophagy in vascular smooth muscle cells. Atherosclerosis 343, 10-19
35078016   Curated Info