Ser1200
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Home > Phosphorylation Site Page: > Ser1200  -  IBTK (human)

Site Information
ASSLHsVsSksFRDF   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 21358401

In vivo Characterization
Methods used to characterize site in vivo:
[32P] ATP in vitro ( 1 ) , immunoprecipitation ( 1 ) , mass spectrometry (in vitro) ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Disease tissue studied:
lymphoma ( 1 ) , B cell lymphoma ( 1 )
Relevant cell line - cell type - tissue:
B lymphocyte-spleen ( 1 ) , DeFew (B lymphocyte) ( 1 ) , DT40 (B lymphocyte) ( 1 ) , HEK293T (epithelial) ( 1 )

Upstream Regulation
Putative in vivo kinases:
PKCB (human) ( 1 )
Kinases, in vitro:
PKCB (human) ( 1 )

Downstream Regulation
Effects of modification on IBTK:
activity, induced ( 1 ) , enzymatic activity, induced ( 1 ) , intracellular localization ( 1 ) , molecular association, regulation ( 1 )
Inhibit interaction with:
Btk (human) ( 1 )

References 

1

Janda E, et al. (2011) Btk regulation in human and mouse B cells via protein kinase C phosphorylation of IBtkγ. Blood 117, 6520-31
21482705   Curated Info

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