Ser17

Site Information
GGPLRsAsPHRSAYE SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 455340

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 ) , phospho-antibody ( 2 )
Relevant cell line - cell type - tissue:	'3T3-L1, differentiated' (adipocyte) ( 1 ) , 'brain, neostriatum' ( 2 )

Upstream Regulation
Putative in vivo kinases:	CDK5 (mouse) ( 2 )
Kinases, in vitro:	CDK5 (mouse) ( 2 )
Treatments:	allosterpaullone ( 2 ) , butyrolactone ( 2 ) , calyculin_A ( 2 ) , ciclosporin ( 2 ) , okadaic_acid ( 2 ) , purvalanol ( 2 ) , seliciclib ( 2 )

References
1	Parker BL, et al. (2015) Targeted phosphoproteomics of insulin signaling using data-independent acquisition mass spectrometry. Sci Signal 8, rs6 26060331 Curated Info
2	Futter M, et al. (2005) Phosphorylation of spinophilin by ERK and cyclin-dependent PK 5 (Cdk5). Proc Natl Acad Sci U S A 102, 3489-94 15728359 Curated Info