Ser569
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Home > Phosphorylation Site Page: > Ser569  -  Kv4.3 (rat)

Site Information
LPATRLRsMQELSTI   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 455338

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 , 2 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 1 , 2 )

Upstream Regulation
Putative in vivo kinases:
p90RSK (human) ( 1 )
Kinases, in vitro:
CAMK2A (rat) ( 2 ) , p90RSK (human) ( 1 )
Treatments:
fluoromethylketone ( 1 ) , H2O2 ( 1 )

Downstream Regulation
Effects of modification on Kv4.3:
activity, inhibited ( 1 )

References 

1

Lu Z, et al. (2008) Reactive oxygen species-induced activation of p90 ribosomal S6 kinase prolongs cardiac repolarization through inhibiting outward K+ channel activity. Circ Res 103, 269-78
18599872   Curated Info

2

Sergeant GP, et al. (2005) Regulation of Kv4.3 currents by Ca2+/calmodulin-dependent protein kinase II. Am J Physiol Cell Physiol 288, C304-13
15456698   Curated Info

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