Thr1548
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Home > Phosphorylation Site Page: > Thr1548  -  LRP6 (human)

Site Information
yAPsRRMtSVATAkG   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 21009100

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 1 )

Upstream Regulation
Kinases, in vitro:
PKACA (human) ( 1 )

Downstream Regulation
Effects of modification on LRP6:
intracellular localization ( 1 ) , molecular association, regulation ( 1 )
Induce interaction with:
G-alpha(s) (human) ( 1 )

References 

1

Wan M, et al. (2011) LRP6 mediates cAMP generation by G protein-coupled receptors through regulating the membrane targeting of Gα(s). Sci Signal 4, ra15
21406690   Curated Info