Thr1548

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Home > Phosphorylation Site Page: > Thr1548 - LRP6 (human)

Site Information
YAPSRRMtSVATAKG SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 21009100

In vivo Characterization
Methods used to characterize site in vivo:	mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:	293 (epithelial) ( 1 )

Upstream Regulation
Kinases, in vitro:	PKACA (human) ( 1 )

Downstream Regulation
Effects of modification on LRP6:	intracellular localization ( 1 ) , molecular association, regulation ( 1 )
Induce interaction with:	G-alpha(s) (human) ( 1 )

References
1	Wan M, et al. (2011) LRP6 mediates cAMP generation by G protein-coupled receptors through regulating the membrane targeting of Gα(s). Sci Signal 4, ra15 21406690 Curated Info

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