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Site Information |
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LPKDLRGtEIYMSPE SwissProt Entrez-Gene |
Blast this site against: NCBI SwissProt PDB |
Site Group ID: 455276 |
In vivo Characterization | |
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Methods used to characterize site in vivo: | |
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Upstream Regulation | |
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Regulatory protein: | |
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Downstream Regulation | |
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Effects of modification on Cot: | |
Effects of modification on biological processes: |
References | |
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Hao J, et al. (2020) Foot-and-Mouth Disease Virus Capsid Protein VP1 Antagonizes TPL2-Mediated Activation of the IRF3/IFN-β Signaling Pathway to Facilitate the Virus Replication. Front Immunol 11, 580334
33488582 Curated Info |
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Robinson MJ, et al. (2007) Phosphorylation of TPL-2 on serine 400 is essential for lipopolysaccharide activation of extracellular signal-regulated kinase in macrophages. Mol Cell Biol 27, 7355-64
17709378 Curated Info |
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Cho J, Melnick M, Solidakis GP, Tsichlis PN (2005) Tpl2 (tumor progression locus 2) phosphorylation at Thr290 is induced by lipopolysaccharide via an Ikappa-B Kinase-beta-dependent pathway and is required for Tpl2 activation by external signals. J Biol Chem 280, 20442-8
15778223 Curated Info |