Thr144
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Home > Phosphorylation Site Page: > Thr144  -  CTBP1 (human)

Site Information
LNLYRRAtWLHQALR   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 2089802

In vivo Characterization
Methods used to characterize site in vivo:
[32P] ATP in vitro ( 1 ) , immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
NCI-H295R ( 1 )

Upstream Regulation
Kinases, in vitro:
PKACA (human) ( 1 )

Downstream Regulation
Effects of modification on CTBP1:
molecular association, regulation ( 1 ) , protein conformation ( 1 )
Effects of modification on biological processes:
transcription, induced ( 1 )
Induce interaction with:
CTBP2 (human) ( 1 )
Inhibit interaction with:
GCN5 (human) ( 1 )

References 

1

Dammer EB, Sewer MB (2008) Phosphorylation of CtBP1 by cAMP-dependent protein kinase modulates induction of CYP17 by stimulating partnering of CtBP1 and 2. J Biol Chem 283, 6925-34
18184656   Curated Info

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