Thr31
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Home > Phosphorylation Site Page: > Thr31  -  AA-NAT (sheep)

Site Information
PGRQRRHtLPANEFR   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 452141

In vivo Characterization
Methods used to characterize site in vivo:
phospho-antibody ( 2 ) , western blotting ( 2 )
Relevant cell line - cell type - tissue:
pineal gland ( 2 )

Upstream Regulation
Kinases, in vitro:
PKACA (human) ( 1 , 2 )
Treatments:
light ( 2 )

Downstream Regulation
Effects of modification on AA-NAT:
enzymatic activity, induced ( 1 , 2 ) , molecular association, regulation ( 1 , 2 )
Induce interaction with:
14-3-3 zeta (human) ( 1 ) , 14-3-3 zeta (sheep) ( 2 )

References 

1

Szewczuk LM, et al. (2008) Analysis of serotonin N-acetyltransferase regulation in vitro and in live cells using protein semisynthesis. Biochemistry 47, 10407-19
18771288   Curated Info

2

Ganguly S, et al. (2005) Melatonin synthesis: 14-3-3-dependent activation and inhibition of arylalkylamine N-acetyltransferase mediated by phosphoserine-205. Proc Natl Acad Sci U S A 102, 1222-7
15644438   Curated Info

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