Ser276
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Home > Phosphorylation Site Page: > Ser276  -  AML1 (mouse)

Site Information
VHPATPIsPGRASGM   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 454401

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 2 ) , phospho-antibody ( 1 , 3 ) , western blotting ( 1 , 3 )
Disease tissue studied:
anthrax infection ( 2 ) , leukemia ( 3 )
Relevant cell line - cell type - tissue:
bone marrow ( 3 ) , D43 ( 3 ) , FL ( 3 ) , HEK293T (epithelial) ( 1 ) , spleen ( 2 )

Upstream Regulation
Regulatory protein:
MYH11 (mouse) ( 3 )

Downstream Regulation
Effects of modification on AML1:
protein degradation ( 1 ) , ubiquitination ( 1 )

References 

1

Komeno Y, et al. (2014) Runx1 exon 6-related alternative splicing isoforms differentially regulate hematopoiesis in mice. Blood 123, 3760-9
24771859   Curated Info

2

Manes NP, et al. (2011) Discovery of mouse spleen signaling responses to anthrax using label-free quantitative phosphoproteomics via mass spectrometry. Mol Cell Proteomics 10, M110.000927
21189417   Curated Info

3

Kamikubo Y, et al. (2010) Accelerated leukemogenesis by truncated CBF beta-SMMHC defective in high-affinity binding with RUNX1. Cancer Cell 17, 455-68
20478528   Curated Info