Ser3
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Home > Phosphorylation Site Page: > Ser3  -  AID (mouse)

Site Information
_____MDsLLMKQKK   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 20660600

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Disease tissue studied:
lymphoma ( 1 ) , B cell lymphoma ( 1 )
Relevant cell line - cell type - tissue:
3T3 (fibroblast) ( 1 ) , B lymphocyte ( 1 ) , CH12.LX (B lymphocyte) ( 1 )

Upstream Regulation
Kinases, in vitro:
PKCA (human) ( 1 ) , PKCB (human) ( 1 ) , PKCB iso2 (human) ( 1 ) , PKCD (human) ( 1 ) , PKCE (human) ( 1 ) , PKCG (human) ( 1 ) , PKCI (human) ( 1 ) , PKCT (human) ( 1 ) , PKCZ (human) ( 1 )
Phosphatases, in vitro:
PPP2CA (human) ( 1 )
Treatments:
calyculin_A ( 1 ) , endothall ( 1 ) , okadaic_acid ( 1 )

Downstream Regulation
Effects of modification on AID:
activity, inhibited ( 1 )

References 

1

Gazumyan A, et al. (2011) Amino-terminal phosphorylation of activation-induced cytidine deaminase suppresses c-myc/IgH translocation. Mol Cell Biol 31, 442-9
21135131   Curated Info