Ser388

Site Information
RHGRALQsNPsEREN SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 20652353

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 , 2 , 3 )
Relevant cell line - cell type - tissue:	'3T3-L1, differentiated' (adipocyte) ( 1 ) , liver ( 3 ) , MEF (fibroblast) [p53 (mouse), homozygous knockout] ( 2 )

Upstream Regulation
Regulatory protein:	TSC2 (mouse) ( 2 )
Treatments:	insulin ( 1 )

References
1	Humphrey SJ, et al. (2013) Dynamic Adipocyte Phosphoproteome Reveals that Akt Directly Regulates mTORC2. Cell Metab 17, 1009-20 23684622 Curated Info
2	Hsu PP, et al. (2011) The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling. Science 332, 1317-22 21659604 Curated Info
3	Villén J, Beausoleil SA, Gerber SA, Gygi SP (2007) Large-scale phosphorylation analysis of mouse liver. Proc Natl Acad Sci U S A 104, 1488-93 17242355 Curated Info