Ser161

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Home > Phosphorylation Site Page: > Ser161 - RIPK1 (human)

Site Information
IADLGLAsFkMWskL SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 20536001

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 ) , mass spectrometry (in vitro) ( 1 ) , mutation of modification site ( 1 )
Disease tissue studied:	leukemia ( 1 ) , T cell leukemia ( 1 )
Relevant cell line - cell type - tissue:	Jurkat (T lymphocyte) ( 1 )

Upstream Regulation
Kinases, in vitro:	RIPK1 (human) ( 1 )

Downstream Regulation
Effects of modification on RIPK1:	enzymatic activity, induced ( 1 )

References
1	Degterev A, et al. (2008) Identification of RIP1 kinase as a specific cellular target of necrostatins. Nat Chem Biol 4, 313-21 18408713 Curated Info

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