Tyr277
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Home > Phosphorylation Site Page: > Tyr277  -  NYAP2 (mouse)

Site Information
PEEEEPVyIEMVGNI   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 455101
Associated spectra:  1 CST

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 2 , 3 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
'brain, embryonic' ( 2 ) , 'neuron, cortical'-brain [NYAP2 (mouse), homozygous knockout] ( 1 ) , 293 (epithelial) ( 1 ) , brain ( 3 )

Upstream Regulation
Putative in vivo kinases:
Fyn (mouse) ( 1 )

Downstream Regulation
Effects of modification on NYAP2:
molecular association, regulation ( 1 )
Induce interaction with:
PIK3R1 (mouse) ( 1 )

References 

1

Yokoyama K, et al. (2011) NYAP: a phosphoprotein family that links PI3K to WAVE1 signalling in neurons. EMBO J 30, 4739-54
21946561   Curated Info

2

Guo A (2007) CST Curation Set: 2672; Year: 2007; Biosample/Treatment: tissue, brain/-; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

3

Guo A (2007) CST Curation Set: 2675; Year: 2007; Biosample/Treatment: tissue, brain/LY; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info