Ser610
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.8.2
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Ser610  -  Fe65 (human)

Site Information
ECRVRFLsFLAVGRD   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 2035401

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
CHO (fibroblast) ( 1 )

Upstream Regulation
Kinases, in vitro:
SGK1 (human) ( 1 )

Downstream Regulation
Effects of modification on Fe65:
intracellular localization ( 1 ) , molecular association, regulation ( 1 ) , protein conformation ( 1 )
Inhibit interaction with:
APP (human) ( 1 )

References 

1

Chow WN, et al. (2015) Phosphorylation of FE65 Ser610 by serum- and glucocorticoid-induced kinase 1 modulates Alzheimer's disease amyloid precursor protein processing. Biochem J 470, 303-17
26188042   Curated Info

PhosphoSitePlus® is a registered trademark of Cell Signaling Technology.
Use of PSP data is subject to a formal license agreement. Learn more

©2003-2025 Cell Signaling Technology, Inc.