Ser311
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Home > Phosphorylation Site Page: > Ser311  -  DAPK3 (human)

Site Information
EytIksHssLPPNNS   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 454895

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 4 ) , mass spectrometry ( 1 , 2 , 4 ) , mutation of modification site ( 4 ) , peptide sequencing ( 4 ) , phosphoamino acid analysis ( 4 )
Disease tissue studied:
luminal A breast cancer ( 1 ) , luminal B breast cancer ( 1 ) , breast cancer, triple negative ( 1 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 4 ) , breast ( 1 ) , HeLa (cervical) ( 2 , 4 )

Upstream Regulation
Kinases, in vitro:
DAPK3 (human) ( 3 , 4 )

References 

1

Mertins P, et al. (2016) Proteogenomics connects somatic mutations to signalling in breast cancer. Nature 534, 55-62
27251275   Curated Info

2

Sharma K, et al. (2014) Ultradeep human phosphoproteome reveals a distinct regulatory nature of Tyr and Ser/Thr-based signaling. Cell Rep 8, 1583-94
25159151   Curated Info

3

Hagerty L, et al. (2007) ROCK1 phosphorylates and activates zipper-interacting protein kinase. J Biol Chem 282, 4884-93
17158456   Curated Info

4

Graves PR, Winkfield KM, Haystead TA (2005) Regulation of zipper-interacting protein kinase activity in vitro and in vivo by multisite phosphorylation. J Biol Chem 280, 9363-74
15611134   Curated Info