Thr265
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Home > Phosphorylation Site Page: > Thr265  -  DAPK3 (mouse)

Site Information
KDPKRRMtIAQSLEH   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 454892

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 ) , mutation of modification site ( 2 ) , phospho-antibody ( 2 )
Disease tissue studied:
neuroblastoma ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Kinases, in vitro:
DAPK3 (mouse) ( 2 )
Treatments:
IL-6 ( 2 ) , LIF ( 2 )

Downstream Regulation
Effects of modification on DAPK3:
enzymatic activity, induced ( 2 )
Effects of modification on biological processes:
apoptosis, induced ( 2 )

References 

1

Wang Y, et al. (2011) Spatial phosphoprotein profiling reveals a compartmentalized extracellular signal-regulated kinase switch governing neurite growth and retraction. J Biol Chem 286, 18190-201
21454597   Curated Info

2

Sato N, et al. (2006) Phosphorylation of threonine-265 in Zipper-interacting protein kinase plays an important role in its activity and is induced by IL-6 family cytokines. Immunol Lett 103, 127-34
16325270   Curated Info