Tyr1363
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Home > Phosphorylation Site Page: > Tyr1363  -  DCC (human)

Site Information
AIEPKVPyTPLLSQP   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 1979800

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 , 2 ) , mutation of modification site ( 2 ) , phospho-antibody ( 2 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 1 , 2 )

Upstream Regulation
Treatments:
netrin-1 ( 2 )

Downstream Regulation
Effects of modification on DCC:
molecular association, regulation ( 1 , 2 )
Induce interaction with:
Fyn (human) ( 2 ) , Lck (human) ( 2 ) , RASA1 (human) ( 1 )

References 

1

Antoine-Bertrand J, et al. (2016) p120RasGAP Protein Mediates Netrin-1 Protein-induced Cortical Axon Outgrowth and Guidance. J Biol Chem 291, 4589-602
26710849   Curated Info

2

Ren XR, et al. (2008) Tyrosine phosphorylation of netrin receptors in netrin-1 signaling. Neurosignals 16, 235-45
18253061   Curated Info

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