Thr133
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Home > Phosphorylation Site Page: > Thr133  -  RASGRP3 (human)

Site Information
YDWMRRVtQRKKVSK   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 454419

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Disease tissue studied:
lymphoma ( 1 ) , Burkitt's lymphoma ( 1 )
Relevant cell line - cell type - tissue:
RAMOS (B lymphocyte) ( 1 ) , Rat2 (fibroblast) ( 1 )

Upstream Regulation
Putative in vivo kinases:
PKCT (human) ( 1 )
Kinases, in vitro:
PKCD (human) ( 1 ) , PKCT (human) ( 1 )
Treatments:
anti-IgM ( 1 ) , Go_6976 ( 1 ) , phorbol_ester ( 1 ) , Ro31-8220 ( 1 )

References 

1

Zheng Y, et al. (2005) Phosphorylation of RasGRP3 on threonine 133 provides a mechanistic link between PKC and Ras signaling systems in B cells. Blood 105, 3648-54
15657177   Curated Info

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