Thr133

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Home > Phosphorylation Site Page: > Thr133 - RASGRP3 (chicken)

Site Information
YDWMRRVtQRKKISK SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 454419

In vivo Characterization
Methods used to characterize site in vivo:	mutation of modification site ( 1 ) , phospho-antibody ( 1 )
Relevant cell line - cell type - tissue:	DT40 (B lymphocyte) ( 1 ) , HEK293T (epithelial) ( 1 )

Upstream Regulation
Putative in vivo kinases:	PKCB (human) ( 1 )

Downstream Regulation
Effects of modification on RASGRP3:	activity, induced ( 1 )

References
1	Aiba Y, et al. (2004) Activation of RasGRP3 by phosphorylation of Thr-133 is required for B cell receptor-mediated Ras activation. Proc Natl Acad Sci U S A 101, 16612-7 15545601 Curated Info

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