Tyr1418
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Home > Phosphorylation Site Page: > Tyr1418  -  DCC (rat)

Site Information
TEDPASVyEQDDLSE   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 454409

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 2 ) , phospho-antibody ( 1 , 2 ) , western blotting ( 2 )
Relevant cell line - cell type - tissue:
'neuron, cerebellar granule'-brain ( 2 ) , 'neuron, cortical'-brain ( 1 ) , oocyte [CPEB (mouse)] ( 2 )

Upstream Regulation
Kinases, in vitro:
Fyn (human) ( 2 )
Treatments:
netrin-1 ( 1 , 2 ) , PP2 ( 2 ) , SU6656 ( 2 )

Downstream Regulation
Effects of modification on biological processes:
cell growth, altered ( 1 , 2 )

References 

1

Ren XR, et al. (2008) Tyrosine phosphorylation of netrin receptors in netrin-1 signaling. Neurosignals 16, 235-45
18253061   Curated Info

2

Meriane M, et al. (2004) Phosphorylation of DCC by Fyn mediates Netrin-1 signaling in growth cone guidance. J Cell Biol 167, 687-98
15557120   Curated Info