Lys2154

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Home > Acetylation Site Page: > Lys2154 - Notch 1 (mouse)

Site Information
kARkPsTkGLACGSk SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 18899513

In vivo Characterization
Methods used to characterize site in vivo:	immunoprecipitation ( 1 ) , mass spectrometry ( 1 ) , modification-specific antibody ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:	293 (epithelial) ( 1 )

Downstream Regulation
Effects of modification on Notch 1:	protein stabilization ( 1 ) , ubiquitination ( 1 )

References
1	Guarani V, et al. (2011) Acetylation-dependent regulation of endothelial Notch signalling by the SIRT1 deacetylase. Nature 473, 234-8 21499261 Curated Info

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