Lys2160
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Home > Acetylation Site Page: > Lys2160  -  Notch 1 (human)

Site Information
VQGKkVRkPsSkGLA   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 18899502

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 1 ) , T lymphocyte-spleen ( 1 )

Upstream Regulation
Treatments:
siRNA ( 1 )

Downstream Regulation
Effects of modification on Notch 1:
intracellular localization ( 1 )
Effects of modification on biological processes:
apoptosis, inhibited ( 1 ) , cell growth, induced ( 1 )

References 

1

Marcel N, Perumalsamy LR, Shukla SK, Sarin A (2017) The lysine deacetylase Sirtuin 1 modulates the localization and function of the Notch1 receptor in regulatory T cells. Sci Signal 10
28377411   Curated Info

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