Ser20
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Home > Phosphorylation Site Page: > Ser20  -  TWIST1 (human)

Site Information
ADDSLsNsEEEPDRQ   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 18899300

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 )
Disease tissue studied:
cancer, squamous cell carcinoma ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
CK2A1 (human) ( 1 )
Kinases, in vitro:
CK2A1 (human) ( 1 )
Treatments:
IL-6 ( 1 ) , Tocilizumab ( 1 )

Downstream Regulation
Effects of modification on TWIST1:
protein stabilization ( 1 )
Effects of modification on biological processes:
carcinogenesis, altered ( 1 ) , cell motility, altered ( 1 )

References 

1

Su YW, Xie TX, Sano D, Myers JN (2011) IL-6 Stabilizes Twist and Enhances Tumor Cell Motility in Head and Neck Cancer Cells through Activation of Casein Kinase 2. PLoS One 6, e19412
21559372   Curated Info