Lys83
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Home > Acetylation Site Page: > Lys83  -  cGAS (human)

Site Information
ATGARAKkAPQRAQD   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 1886859302

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 ) , modification-specific antibody ( 1 ) , mutation of modification site ( 1 )
Disease tissue studied:
leukemia ( 1 ) , acute myelogenous leukemia ( 1 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 1 ) , THP1 (myeloid) ( 1 )

Upstream Regulation
Treatments:
siRNA ( 1 ) , virus infection ( 1 )

Downstream Regulation
Effects of modification on cGAS:
molecular association, regulation ( 1 )
Effects of modification on biological processes:
transcription, induced ( 1 )
Induce interaction with:
DNA ( 1 )

References 

1

Song ZM, et al. (2020) KAT5 acetylates cGAS to promote innate immune response to DNA virus. Proc Natl Acad Sci U S A
32817552   Curated Info

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