Lys138

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Home > Acetylation Site Page: > Lys138 - PYHIN1 (human)

Site Information
EETLGPQkRKKPsEE SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 1881258603

In vivo Characterization
Methods used to characterize site in vivo:	immunoprecipitation ( 1 ) , mass spectrometry ( 1 ) , mutation of modification site ( 1 )
Disease tissue studied:	bone cancer ( 1 )
Relevant cell line - cell type - tissue:	293 (epithelial) ( 1 ) , U2OS (bone cell) ( 1 )

Downstream Regulation
Effects of modification on PYHIN1:	intracellular localization ( 1 )

References
1	Howard TR, et al. (2021) The DNA Sensor IFIX Drives Proteome Alterations To Mobilize Nuclear and Cytoplasmic Antiviral Responses, with Its Acetylation Acting as a Localization Toggle. mSystems 6, e0039721 34156286 Curated Info

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