Arg124

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Home > Di-methylation Site Page: > Arg124 - cGAS (human)

Site Information
RAGsCRQrGARCsTK SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 1881215700

In vivo Characterization
Methods used to characterize site in vivo:	immunoprecipitation ( 1 ) , mass spectrometry ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:	HEK293T (epithelial) ( 1 ) , macrophage-bone marrow ( 1 ) , MEF (fibroblast) ( 1 )

Upstream Regulation
Treatments:	EPZ015666 ( 1 )

Downstream Regulation
Effects of modification on cGAS:	molecular association, regulation ( 1 )
Inhibit interaction with:	DNA ( 1 )

References
1	Ma D, et al. (2021) Arginine methyltransferase PRMT5 negatively regulates cGAS-mediated antiviral immune response. Sci Adv 7 33762328 Curated Info

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