Lys435

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Home > Acetylation Site Page: > Lys435 - SQSTM1 (human)

Site Information
LDtIQyskHPPPL__ SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 1879848303

In vivo Characterization
Methods used to characterize site in vivo:	immunoprecipitation ( 1 ) , mass spectrometry ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:	293 (epithelial) ( 1 ) , HEK293T (epithelial) ( 1 ) , HeLa (cervical) ( 1 )

Downstream Regulation
Effects of modification on SQSTM1:	molecular association, regulation ( 1 )
Induce interaction with:	ubiquitin (human) ( 1 )
Inhibit interaction with:	SQSTM1 (human) ( 1 )

References
1	You Z, et al. (2019) Requirement for p62 acetylation in the aggregation of ubiquitylated proteins under nutrient stress. Nat Commun 10, 5792 31857589 Curated Info

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