Lys6

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Home > Ubiquitylation Site Page: > Lys6 - Huntingtin (human)

Site Information
__MAtLEkLMkAFEs SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 1877148902

In vivo Characterization
Methods used to characterize site in vivo:	mutation of modification site ( 1 )
Disease tissue studied:	Huntington's disease ( 1 )
Relevant cell line - cell type - tissue:	'neuron, cortical'-brain ( 1 )

Downstream Regulation
Effects of modification on Huntingtin:	ubiquitination ( 1 )

References
1	Hakim-Eshed V, et al. (2020) Site-specific ubiquitination of pathogenic huntingtin attenuates its deleterious effects. Proc Natl Acad Sci U S A 117, 18661-18669 32675242 Curated Info

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