Lys94
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Home > Sumoylation Site Page: > Lys94  -  OBFC2B (human)

Site Information
GRGGDLQkIGEFCMV   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 1877008702

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , western blotting ( 1 )
Disease tissue studied:
bone cancer ( 1 ) , colorectal cancer ( 1 ) , colorectal carcinoma ( 1 )
Relevant cell line - cell type - tissue:
HCT116 (intestinal) ( 1 ) , HEK293T (epithelial) ( 1 ) , HeLa (cervical) ( 1 ) , U2OS (bone cell) ( 1 )

Upstream Regulation
Treatments:
etoposide ( 1 )

Downstream Regulation
Effects of modification on OBFC2B:
molecular association, regulation ( 1 ) , protein stabilization ( 1 )
Effects of modification on biological processes:
apoptosis, induced ( 1 )
Induce interaction with:
NBS1 (human) ( 1 )

References 

1

Zhou L, et al. (2020) SUMOylation stabilizes hSSB1 and enhances the recruitment of NBS1 to DNA damage sites. Signal Transduct Target Ther 5, 80
32576812   Curated Info

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