Lys442

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Home > Sumoylation Site Page: > Lys442 - SCN5A (human)

Site Information
QEAMEMLkkEHEALT SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 1877008700

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 )
Relevant cell line - cell type - tissue:	CHO-K1 (fibroblast) ( 1 ) , myocyte ( 1 )

Upstream Regulation
Treatments:	hypoxia ( 1 )

Downstream Regulation
Effects of modification on SCN5A:	activity, induced ( 1 )

References
1	Plant LD, et al. (2020) Hypoxia Produces Pro-arrhythmic Late Sodium Current in Cardiac Myocytes by SUMOylation of Na1.5 Channels. Cell Rep 30, 2225-2236.e4 32075761 Curated Info

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