Thr369
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Home > Phosphorylation Site Page: > Thr369  -  NRF2 (human)

Site Information
ESSSYGDtLLGLsDs   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 1876350200

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
HEK293T (epithelial) ( 1 ) , hepatocyte-liver ( 1 )

Upstream Regulation
Putative in vivo kinases:
PAK4 (human) ( 1 )
Kinases, in vitro:
PAK4 (human) ( 1 )
Treatments:
ND201651 ( 1 )

Downstream Regulation
Effects of modification on NRF2:
intracellular localization ( 1 ) , protein degradation ( 1 ) , ubiquitination ( 1 )
Effects of modification on biological processes:
apoptosis, induced ( 1 ) , transcription, inhibited ( 1 )

References 

1

Mao Y, et al. (2022) PAK4 inhibition protects against liver ischemia/reperfusion injury: Role of Nrf2 phosphorylation. Hepatology
35108418   Curated Info