Lys234
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Home > Sumoylation Site Page: > Lys234  -  Snail1 (human)

Site Information
LQTHSDVkkYQCQAC   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 1873356100

In vivo Characterization
Methods used to characterize site in vivo:
immunoassay ( 1 ) , immunoprecipitation ( 1 ) , modification-specific antibody ( 1 ) , western blotting ( 1 )
Disease tissue studied:
breast cancer ( 1 ) , lung cancer ( 1 ) , non-small cell lung cancer ( 1 ) , non-small cell lung adenocarcinoma ( 1 ) , prostate cancer ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Treatments:
TGF-beta ( 1 )

Downstream Regulation
Effects of modification on Snail1:
intracellular localization ( 1 ) , molecular association, regulation ( 1 )
Effects of modification on biological processes:
carcinogenesis, induced ( 1 ) , cell motility, induced ( 1 ) , transcription, induced ( 1 )
Induce interaction with:
Jun (human) ( 1 )

References 

1

Gudey SK, et al. (2017) Pro-invasive properties of Snail1 are regulated by sumoylation in response to TGFβ stimulation in cancer. Oncotarget 8, 97703-97726
29228645   Curated Info