Ser267
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Home > Phosphorylation Site Page: > Ser267  -  Abi-1 (human)

Site Information
PIAVPtPsPPTIGPE   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 18715503

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
COS (fibroblast) ( 1 )

Upstream Regulation
Putative in vivo kinases:
ERK1 (human) ( 1 ) , ERK2 (human) ( 1 )

Downstream Regulation
Effects of modification on Abi-1:
molecular association, regulation ( 1 )
Effects of modification on biological processes:
cell motility, altered ( 1 ) , cytoskeletal reorganization ( 1 )

References 

1

Mendoza MC, et al. (2011) ERK-MAPK Drives Lamellipodia Protrusion by Activating the WAVE2 Regulatory Complex. Mol Cell 41, 661-71
21419341   Curated Info

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