Ser264
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Home > Phosphorylation Site Page: > Ser264  -  SMAD3 (human)

Site Information
VDGFTDPsNSERFCL   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 1868957100

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:

Downstream Regulation
Effects of modification on SMAD3:
activity, inhibited ( 1 ) , phosphorylation ( 1 ) , protein stabilization ( 1 )
Effects of modification on biological processes:
cell differentiation, inhibited ( 1 ) , cell growth, induced ( 1 ) , signaling pathway regulation ( 1 ) , transcription, inhibited ( 1 )

References 

1

Kang H, et al. (2020) Somatic SMAD3-activating mutations cause melorheostosis by up-regulating the TGF-β/SMAD pathway. J Exp Med 217
32232430   Curated Info