Thr386
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Home > Phosphorylation Site Page: > Thr386  -  VRK1 (human)

Site Information
QtEEAIQtRSRTRKR   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 1868585000

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry (in vitro) ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Disease tissue studied:
liver cancer ( 1 ) , hepatocellular carcinoma ( 1 )
Relevant cell line - cell type - tissue:
Huh7 (hepatic) ( 1 )

Upstream Regulation
Regulatory protein:
plakophilin 2 (human) ( 1 )
Putative in vivo kinases:
VRK1 (human) ( 1 )
Kinases, in vitro:
VRK1 (human) ( 1 )
Treatments:
low_glucose ( 1 ) , UV ( 1 )

Downstream Regulation
Effects of modification on VRK1:
phosphorylation ( 1 )

References 

1

Yokobori K, Miyauchi Y, Williams JG, Negishi M (2020) Phosphorylation of vaccinia-related kinase 1 at threonine 386 transduces glucose stress signal in human liver cells. Biosci Rep 40
32266931   Curated Info

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