Ser351
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Home > Phosphorylation Site Page: > Ser351  -  KOR-3 (human)

Site Information
QVsDRVRsIAKDVAL   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 1868135701

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 1 ) , brain ( 1 ) , central nervous tissue ( 1 )

Upstream Regulation
Putative in vivo kinases:
GRK2 (human) ( 1 ) , GRK3 (human) ( 1 )
Treatments:
AT202 ( 1 ) , cebranopadol ( 1 ) , compound_101 ( 1 ) , J113397 ( 1 ) , MCOPPB ( 1 ) , NKH_477 ( 1 ) , NNC 63-0532 ( 1 ) , nociceptin ( 1 ) , phorbol_ester ( 1 ) , Ro64-6198 ( 1 ) , SB 612111 ( 1 ) , SCH221510 ( 1 ) , siRNA ( 1 )

Downstream Regulation
Effects of modification on KOR-3:
receptor desensitization, induced ( 1 ) , receptor internalization, induced ( 1 )
Effects of modification on biological processes:
signaling pathway regulation ( 1 )

References 

1

Mann A, et al. (2019) Agonist-selective NOP receptor phosphorylation correlates in vitro and in vivo and reveals differential post-activation signaling by chemically diverse agonists. Sci Signal 12
30914485   Curated Info