Thr411

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Home > Phosphorylation Site Page: > Thr411 - TNF-R1 (human)

Site Information
LAtWRRRtPRREAtL SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 1868023606

In vivo Characterization
Methods used to characterize site in vivo:	mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:	HEK293T (epithelial) ( 1 )

Upstream Regulation
Putative in vivo kinases:	PKACA (human) ( 1 )

Downstream Regulation
Effects of modification on TNF-R1:	molecular association, regulation ( 1 ) , phosphorylation ( 1 )
Effects of modification on biological processes:	apoptosis, induced ( 1 ) , signaling pathway regulation ( 1 )
Inhibit interaction with:	GRB2 (human) ( 1 )

References
1	Hapil FZ, et al. (2020) Negative Regulation of TNFR1 Signaling Via PKA-Mediated Phosphorylation of TNFR1. J Interferon Cytokine Res 32159413 Curated Info

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