Tyr292
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Home > Phosphorylation Site Page: > Tyr292  -  IRF3 (human)

Site Information
RLGHCHTyWAVSEEL   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 1867930600

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mass spectrometry ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
Abl (human) ( 1 ) , Arg (human) ( 1 )
Treatments:
nilotinib ( 1 )

Downstream Regulation
Effects of modification on IRF3:
activity, induced ( 1 )
Effects of modification on biological processes:
transcription, induced ( 1 )

References 

1

Luo F, et al. (2019) Nonreceptor Tyrosine Kinase c-Abl- and Arg-Mediated IRF3 Phosphorylation Regulates Innate Immune Responses by Promoting Type I IFN Production. J Immunol 202, 2254-2265
30842273   Curated Info