Ser350
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Home > Phosphorylation Site Page: > Ser350  -  5-HT(6) (human)

Site Information
ERQAsLAsPSLRTSH   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 1867750504

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 )
Disease tissue studied:
neuroblastoma ( 1 )
Relevant cell line - cell type - tissue:
brain ( 1 ) , NG108-15 (neuron) ( 1 )

Upstream Regulation
Regulatory protein:
CDK5R1 (human) ( 1 )
Putative in vivo kinases:
CDK5 (human) ( 1 )

Downstream Regulation
Effects of modification on 5-HT(6):
activity, inhibited ( 1 ) , enzymatic activity, induced ( 1 ) , molecular association, regulation ( 1 )
Effects of modification on biological processes:
cell growth, induced ( 1 )
Inhibit interaction with:
GRIN1 (human) ( 1 )

References 

1

Pujol CN, et al. (2020) Dynamic interactions of the 5-HT receptor with protein partners control dendritic tree morphogenesis. Sci Signal 13
32047117   Curated Info