Ser641

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Home > Phosphorylation Site Page: > Ser641 - HCN2 (mouse)

Site Information
DRIGKKNsILLHKVQ SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 18454000

In vivo Characterization
Methods used to characterize site in vivo:	immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:	293 (epithelial) ( 1 ) , neuron-'brain, hippocampus' ( 1 )

Upstream Regulation
Putative in vivo kinases:	PKG2 (human) ( 1 )

Downstream Regulation
Effects of modification on HCN2:	activity, inhibited ( 1 )

References
1	Hammelmann V, et al. (2011) The cGMP-Dependent Protein Kinase II Is an Inhibitory Modulator of the Hyperpolarization-Activated HCN2 Channel. PLoS One 6, e17078 21347269 Curated Info

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