Ser724
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Home > Phosphorylation Site Page: > Ser724  -  FOXM1 iso2 (human)

Site Information
SKILLDIsFPGLDED   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 18009877

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Disease tissue studied:
bone cancer ( 1 )
Relevant cell line - cell type - tissue:
U2OS (bone cell) ( 1 )

Upstream Regulation
Putative in vivo kinases:
PLK1 (human) ( 1 )
Kinases, in vitro:
PLK1 (human) ( 1 )

Downstream Regulation
Effects of modification on FOXM1 iso2:
intracellular localization ( 1 ) , sumoylation ( 1 )
Effects of modification on biological processes:
cell cycle regulation ( 1 ) , transcription, induced ( 1 )

References 

1

Zhang J, et al. (2015) Polo-like Kinase 1-mediated Phosphorylation of Forkhead Box Protein M1b Antagonizes Its SUMOylation and Facilitates Its Mitotic Function. J Biol Chem 290, 3708-19
25533473   Curated Info

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