Ser2

Site Information
______MsLGGVSEA SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 18261387

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 2 , 3 )
Disease tissue studied:	melanoma skin cancer ( 3 )
Relevant cell line - cell type - tissue:	macrophage-bone marrow ( 2 ) , macrophage-bone marrow [DUSP1 (mouse), homozygous knockout] ( 2 ) , skin [mGluR1 (mouse), transgenic, TG mutant mice] ( 3 )

Upstream Regulation
Treatments:	LPS ( 2 )

References
1	Mertins P, et al. (2014) Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels. Mol Cell Proteomics 13, 1690-704 24719451 Curated Info
2	Weintz G, et al. (2010) The phosphoproteome of toll-like receptor-activated macrophages. Mol Syst Biol 6, 371 20531401 Curated Info
3	Zanivan S, et al. (2008) Solid tumor proteome and phosphoproteome analysis by high resolution mass spectrometry. J Proteome Res 7, 5314-26 19367708 Curated Info