Ser364

Site Information
RQNEHEVsPRMELsP SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 18261067

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 , 3 , 4 , 5 )
Disease tissue studied:	melanoma skin cancer ( 5 )
Relevant cell line - cell type - tissue:	heart ( 3 ) , liver ( 1 , 4 ) , liver [leptin (mouse), homozygous knockout] ( 4 ) , skin [mGluR1 (mouse), transgenic, TG mutant mice] ( 5 )

Upstream Regulation
Regulatory protein:	ADRB1 (mouse) ( 3 )

References
1	Robles MS, Humphrey SJ, Mann M (2017) Phosphorylation Is a Central Mechanism for Circadian Control of Metabolism and Physiology. Cell Metab 25, 118-127 27818261 Curated Info
2	Mertins P, et al. (2014) Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels. Mol Cell Proteomics 13, 1690-704 24719451 Curated Info
3	Lundby A, et al. (2013) In vivo phosphoproteomics analysis reveals the cardiac targets of β-adrenergic receptor signaling. Sci Signal 6, rs11 23737553 Curated Info
4	Grimsrud PA, et al. (2012) A quantitative map of the liver mitochondrial phosphoproteome reveals posttranslational control of ketogenesis. Cell Metab 16, 672-83 23140645 Curated Info
5	Zanivan S, et al. (2008) Solid tumor proteome and phosphoproteome analysis by high resolution mass spectrometry. J Proteome Res 7, 5314-26 19367708 Curated Info