Ser130

Site Information
LHMERVIsYEEGkAL SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 18157800

In vivo Characterization
Methods used to characterize site in vivo:	[32P] ATP in vitro ( 1 ) , immunoprecipitation ( 1 ) , mass spectrometry (in vitro) ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:	293 (epithelial) ( 1 ) , E.coli (bacterial) ( 1 ) , MEF (fibroblast) ( 1 )

Downstream Regulation
Effects of modification on RHEB:	activity, inhibited ( 1 ) , phosphorylation ( 1 )
Inhibit interaction with:	Other ( 1 )

References
1	Zheng M, et al. (2011) Inactivation of Rheb by PRAK-mediated phosphorylation is essential for energy-depletion-induced suppression of mTORC1. Nat Cell Biol 13, 263-72 21336308 Curated Info