Thr102
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Home > Phosphorylation Site Page: > Thr102  -  JunB (human)

Site Information
SNGVITTtPtPPGQy   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 1814001

In vivo Characterization
Methods used to characterize site in vivo:
electrophoretic mobility shift ( 4 ) , mass spectrometry ( 1 , 2 , 3 ) , mutation of modification site ( 4 )
Disease tissue studied:
breast cancer ( 1 ) , cervical cancer ( 2 ) , cervical adenocarcinoma ( 2 ) , lymphoma ( 4 ) , B cell lymphoma ( 4 )
Relevant cell line - cell type - tissue:
HeLa (cervical) ( 3 ) , HeLa S3 (cervical) ( 2 ) , HMLER ('stem, breast cancer') ( 1 ) , HMLER ('stem, breast cancer') [CXCR4 (human), knockdown] ( 1 ) , M12 (B lymphocyte) ( 4 ) , T lymphocyte-lymph node ( 4 )

Upstream Regulation
Putative in vivo kinases:
JNK1 (mouse) ( 4 )
Kinases, in vitro:
JNK1 (human) ( 4 )
Treatments:
ionomycin ( 4 ) , nocodazole ( 2 ) , phorbol_ester ( 4 )

Downstream Regulation
Effects of modification on JunB:
activity, induced ( 4 ) , molecular association, regulation ( 4 )
Effects of modification on biological processes:
transcription, altered ( 4 )
Induce interaction with:
DNA ( 4 )

References 

1

Yi T, et al. (2014) Quantitative phosphoproteomic analysis reveals system-wide signaling pathways downstream of SDF-1/CXCR4 in breast cancer stem cells. Proc Natl Acad Sci U S A 111, E2182-90
24782546   Curated Info

2

Olsen JV, et al. (2010) Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. Sci Signal 3, ra3
20068231   Curated Info

3

Dephoure N, et al. (2008) A quantitative atlas of mitotic phosphorylation. Proc Natl Acad Sci U S A 105, 10762-7
18669648   Curated Info

4

Li B, Tournier C, Davis RJ, Flavell RA (1999) Regulation of IL-4 expression by the transcription factor JunB during T helper cell differentiation. EMBO J 18, 420-32
9889198   Curated Info