Thr103
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Home > Phosphorylation Site Page: > Thr103  -  SND1 (human)

Site Information
CFtIENktPQGrEyG   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 18015998

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mass spectrometry ( 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Disease tissue studied:
breast cancer ( 4 ) , luminal A breast cancer ( 2 ) , luminal B breast cancer ( 2 ) , breast cancer, triple negative ( 2 , 4 ) , cervical cancer ( 8 ) , cervical adenocarcinoma ( 8 )
Relevant cell line - cell type - tissue:
breast ( 2 , 4 ) , HeLa (cervical) ( 1 , 3 , 6 , 7 ) , HeLa S3 (cervical) ( 8 ) , Jurkat (T lymphocyte) ( 5 ) , K562 (erythroid) ( 6 )

Upstream Regulation
Putative in vivo kinases:
JNK1 (human) ( 1 )
Kinases, in vitro:
JNK1 (human) ( 1 )
Treatments:
arsenite ( 1 ) , nocodazole ( 8 )

Downstream Regulation
Effects of modification on SND1:
intracellular localization ( 1 ) , molecular association, regulation ( 1 )
Induce interaction with:
G3BP-1 (human) ( 1 )

References 

1

Su C, et al. (2017) Phosphorylation of Tudor-SN, a novel substrate of JNK, is involved in the efficient recruitment of Tudor-SN into stress granules. Biochim Biophys Acta 1864, 562-571
28011284   Curated Info

2

Mertins P, et al. (2016) Proteogenomics connects somatic mutations to signalling in breast cancer. Nature 534, 55-62
27251275   Curated Info

3

Sharma K, et al. (2014) Ultradeep human phosphoproteome reveals a distinct regulatory nature of Tyr and Ser/Thr-based signaling. Cell Rep 8, 1583-94
25159151   Curated Info

4

Mertins P, et al. (2014) Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels. Mol Cell Proteomics 13, 1690-704
24719451   Curated Info

5

Mertins P, et al. (2013) Integrated proteomic analysis of post-translational modifications by serial enrichment. Nat Methods 10, 634-7
23749302   Curated Info

6

Zhou H, et al. (2013) Toward a comprehensive characterization of a human cancer cell phosphoproteome. J Proteome Res 12, 260-71
23186163   Curated Info

7

Kettenbach AN, et al. (2011) Quantitative phosphoproteomics identifies substrates and functional modules of aurora and polo-like kinase activities in mitotic cells. Sci Signal 4, rs5
21712546   Curated Info

8

Olsen JV, et al. (2010) Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. Sci Signal 3, ra3
20068231   Curated Info