Thr273

Site Information
tEDQTLItkRVMFAY SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 18008351

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 , 2 , 3 )
Disease tissue studied:	cervical cancer ( 2 ) , cervical adenocarcinoma ( 2 ) , esophageal cancer, surrounding tissue ( 3 )
Relevant cell line - cell type - tissue:	esophagus ( 3 ) , HeLa (cervical) ( 1 ) , HeLa S3 (cervical) ( 2 )

Upstream Regulation
Treatments:	BI2536 ( 1 )

References
1	Kettenbach AN, et al. (2011) Quantitative phosphoproteomics identifies substrates and functional modules of aurora and polo-like kinase activities in mitotic cells. Sci Signal 4, rs5 21712546 Curated Info
2	Olsen JV, et al. (2010) Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. Sci Signal 3, ra3 20068231 Curated Info
3	Gu T (2009) CST Curation Set: 7078; Year: 2009; Biosample/Treatment: tissue, esophagus/untreated; Disease: esophageal cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991 Curated Info