Ser707
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.7.9
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Ser707  -  STAT6 (human)

Site Information
IPPYQGLsPEESVNV   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 17772900

In vivo Characterization
Methods used to characterize site in vivo:
electrophoretic mobility shift ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 1 ) , HeLa (cervical) ( 1 )

Upstream Regulation
Putative in vivo kinases:
JNK1 (human) ( 1 )
Kinases, in vitro:
JNK1 (human) ( 1 )
Treatments:
anisomycin ( 1 ) , IFN-gamma ( 1 ) , IL-1b ( 1 ) , siRNA ( 1 ) , SP600125 ( 1 )

Downstream Regulation
Effects of modification on STAT6:
molecular association, regulation ( 1 )
Effects of modification on biological processes:
transcription, inhibited ( 1 )

References 

1

Shirakawa T, et al. (2011) Deactivation of STAT6 through serine 707 phosphorylation by JNK. J Biol Chem 286, 4003-10
21123173   Curated Info

Developed with grants from  NIH Logo and literature mining with Linguamatics  I2E Logo Creative Commons License PhosphoSite, created by Cell Signaling Technology is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License.

©2003-2024 Cell Signaling Technology, Inc.