Ser265
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Home > Phosphorylation Site Page: > Ser265  -  JMJD1A (human)

Site Information
GAVKRKssENNGTLV   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 453894

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 , 2 ) , mass spectrometry ( 2 , 4 , 5 , 6 ) , mutation of modification site ( 1 , 2 ) , phospho-antibody ( 1 , 2 ) , western blotting ( 1 , 2 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Kinases, in vitro:
PKACA (human) ( 2 )
Treatments:
angiotensin_2 ( 6 )

Downstream Regulation
Effects of modification on JMJD1A:
molecular association, regulation ( 1 , 2 )
Effects of modification on biological processes:
transcription, induced ( 1 , 2 )
Induce interaction with:
ARID1A (human) ( 2 ) , PPAR-gamma (human) ( 2 ) , PRDM16 (mouse) ( 1 )

References 

1

Abe Y, et al. (2018) Histone demethylase JMJD1A coordinates acute and chronic adaptation to cold stress via thermogenic phospho-switch. Nat Commun 9, 1566
29674659   Curated Info

2

Abe Y, et al. (2015) JMJD1A is a signal-sensing scaffold that regulates acute chromatin dynamics via SWI/SNF association for thermogenesis. Nat Commun 6, 7052
25948511   Curated Info

3

Beli P, et al. (2012) Proteomic Investigations Reveal a Role for RNA Processing Factor THRAP3 in the DNA Damage Response. Mol Cell 46, 212-25
22424773   Curated Info

4

Guo A (2011) CST Curation Set: 11733; Year: 2011; Biosample/Treatment: cell line, Jurkat/calyculin_A & pervanadate; Disease: T cell leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: RXXp[ST]
Curated Info

5

Rigbolt KT, et al. (2011) System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. Sci Signal 4, rs3
21406692   Curated Info

6

Christensen GL, et al. (2010) Quantitative phosphoproteomics dissection of seven-transmembrane receptor signaling using full and biased agonists. Mol Cell Proteomics 9, 1540-53
20363803   Curated Info