Ser696
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Home > Phosphorylation Site Page: > Ser696  -  HIF1A (human)

Site Information
NVLsVALsQRTtVPE   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 17595900

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 ) , mass spectrometry (in vitro) ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Disease tissue studied:
ataxia-telangiectasia ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
ATM (human) ( 1 )
Kinases, in vitro:
ATM (human) ( 1 )
Treatments:
hypoxia ( 1 )

Downstream Regulation
Effects of modification on HIF1A:
protein stabilization ( 1 )
Effects of modification on biological processes:
transcription, altered ( 1 )

References 

1

Cam H, Easton JB, High A, Houghton PJ (2010) mTORC1 signaling under hypoxic conditions is controlled by ATM-dependent phosphorylation of HIF-1α. Mol Cell 40, 509-20
21095582   Curated Info